UNDERSTANDING CANCER STEM CELLS AND PLASTICITY: TOWARDS BETTER THERAPEUTICS




Combination of farnesyl-transferase inhibition with KRAS G12D targeting breaks down therapeutic resistance in pancreatic cancer

Pancreatic adenocarcinoma is one of the deadliest forms of cancer with no effective therapeutic options.A KRAS mutation can be found in up to 90% of all pancreatic tumors, making it a promising therapeutic target.The introduction of new KRAS inhibitors has been a milestone podocarpus gracilior column in the history of KRAS mutant tumors; however, t

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